Researchers have found that high doses of a drug called favipiravir strongly inhibit SARS-CoV-2 in hamsters. Favipiravir also prevented infection in healthy animals that had exposure to an infected cage mate. It takes many years to develop a potent antiviral drug from scratch for a particular viral infection. Throughout the […]
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SARS-CoV-2, the virus that causes COVID-19, enlists the help of two enzymes on the surface of human cells in order to invade them. A new study suggests that a compound that inhibits both enzymes could make a highly effective treatment. Share on PinterestNew research finds that a drug could keep […]
The drug, called lumefantrine, may improve the success rate of radiation and chemotherapy treatments for a severe type of brain cancer. Glioblastoma multiforme (GBM) is an especially aggressive form of cancer that is difficult to treat. With currently available therapies, the 5-year survival rate for people with GBM is 5.6%. […]
A study combining analysis of patient samples with mice studies has identified new drug targets for alcohol-related liver disease, which, currently, doctors can only treat by transplant. Share on PinterestResearchers find new drug targets for the potential treatment of alcohol-related liver disease. Alcohol-related liver disease (ALD), as its name suggests, […]
Treating obese mice with disulfiram — a drug that doctors usually prescribe for alcohol use disorder — led to significant weight loss and improved metabolic health, a new study reports. Obesity is a major health problem facing societies across the globe. Rates of obesity have almost tripled since 1975, with […]
By mapping interactions between human proteins and the new coronavirus, researchers have pinpointed 29 potential treatments using drugs already approved by the Food and Drug Administration (FDA) for a wide range of other conditions. Share on PinterestScientists have tested an array of pre-existing drugs to see how they might tackle […]
Researchers in Japan have identified lower levels of a critical lipid in the brains of people with schizophrenia, which could lead to new treatments for the brain disorder. Share on PinterestResearchers have found that levels of a critical lipid are lower in the brains of people with schizophrenia. Schizophrenia is […]
A cycle of blood clotting and inflammation may contribute to the breathing difficulties of some COVID-19 patients. A forthcoming clinical trial will assess whether a type of drug already approved for the prevention of blood clots after a heart attack or stroke might help prevent these difficulties. Share on PinterestA […]
The number of COVID-19 cases around the world has just passed 1 million, and it may seem as though this pandemic will never go away. It is important to remember that, in their labs, scientists are making quiet progress every day — helping untangle the causes of this crisis and […]
Researchers have identified a mechanism by which tumors become resistant to cancer drugs. Share on PinterestScientists have identified a mechanism in which cancer cells consume other dead cells to sustain themselves and develop drug resistance. Researchers at the University of California, Irvine, have discovered a new mechanism that explains how […]